---
title: Could Your Genital/Pelvic/Sciatic Pain Be Caused by a Hidden Vascular Problem?
description: Neuropelveology, founded by Prof. Possover, treats pelvic nerve disorders like chronic pain, endometriosis, and spinal injuries using LANN and LION surgical techniques.
---

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# [Could Your Genital/Pelvic/Sciatic Pain Be Caused by a Hidden Vascular Problem?](https://blog.possover.com/en/pelvic-pain-vascular-entrapment)

 Written by [Marc Possover](https://blog.possover.com/en/author/marc-possover) | Apr 19, 2025 11:45:38 AM

Prof. Prof. DK Prof. Dr. med. Marc Possover, MD, PhD

*Understanding the Link Between Autoimmune Disease and Pelvic Neuropathic Pain*

If you are a woman suffering from chronic pelvic, lower back, or sciatic pain - especially if doctors have told you it’s “unexplained” or “psychosomatic” - this article is for you.

At the Possover International Medical Center in Zurich, we’ve uncovered an often-overlooked but treatable cause of pelvic pain: **vascular entrapment of pelvic nerves**, particularly in women with autoimmune and connective tissue disorders like **Ehlers-Danlos Syndrome (EDS), **or blodd diseases with increased risk from thrombosis like **May-Thurner Syndrome, Nutcracker syndrome, Thalassemia** or **Factor V leiden mutation**.

 

**WHAT IS VASCULAR ENTRAPMENT?**

In many women, especially those with autoimmune conditions, **abnormally placed or enlarged blood vessels** can compress pelvic nerves. This is known as *vascular entrapment*, and it may affect:

- The **sciatic nerve** (causing pain down the leg or in the buttock),
- The **pudendal nerve** (causing burning, stabbing, or pressure in the vulva, perineum, or rectal area),
- The **sacral nerves** (causing bladder or bowel dysfunction, genital numbness or hypersensitivity, or deep pelvic pain).

This condition is **not visible on standard MRI scans**, and is often misdiagnosed as endometriosis, interstitial cystitis, irritable bowel syndrome - or simply “chronic pelvic pain syndrome of unknown origin.”

 

**COULD THIS BE YOU?**

Ask yourself:

- Does your pain worsen when **sitting**, during your **period**, or after **intercourse**?
- Does it improve or **disappear at night** when you lie down?
- Have you been diagnosed with Joint Hypermobility Syndrome, **Ehlers-Danlos-Syndrome (EDS)**, **Hashimoto’s thyroiditis**, **Lupus**, or another **autoimmune condition**?
- Do you suffer from **sciatic pain**, **vulvodynia**, or unexplained **bladder issues (Interstitiel Cystitis, chronic UI)**?

If so, your pain may be caused by **vascular entrapment** - and **it’s treatable**.

 

**WHY AUTOIMMUNE DISEASES PLAY A ROLE?**

In a study of 128 women with confirmed pelvic nerve compression at the Possover International Medical center (over the last 2 years), **2 in 3 had an autoimmune disease** — and nearly 52% had EDS or a similar connective tissue disorder.

These conditions can weaken the blood vessels, make them more prone to enlargement, and trigger inflammation that leads to nerve irritation.

In other words: **Your immune system might be contributing to your pain - by affecting your blood vessels and compressing your nerves.**

 

**DIAGNOSIS: WHAT WORKS (AND WHAT DOESN'T)**

Unfortunately, **MRI scans often miss this condition** - not because it isn’t real, but because radiologists aren’t trained to look for it.

Instead, we’ve found that **vaginal sonography with Doppler** - a special ultrasound that shows how blood flows in the pelvic veins - is far more accurate.

Combined with your **symptoms and medical history**, this allows us to identify the exact nerves involved and the location of the compression.

 

**REAL TREATMENT, REAL RESULTS**

With more than 20 years of experience in Neuropelveology, we perform at our center **laparoscopic nerve decompression** - a minimally invasive surgery to release the affected nerves from the surrounding blood vessels. This procedure doe’snt belong Gynecology, but vascular surgery performed by laparoscopy.

After surgery, **over 75% of women report at least a 50% reduction in pain** - many after years, even decades, of suffering without a diagnosis.

“I thought I was going crazy. I had seen over 10 doctors. When Professor Possover finally explained what was going on and treated it, it changed my life.”  
- A former patient

 

**WHY EXPERTISE MATTERS IN VASCULAR ENTRAPMENT SURGERY?**

Surgical treatment for vascular entrapment of pelvic nerves is a **highly delicate and specialized procedure** — it is ***not *gynecologic surgery**, even if it uses laparoscopic access. It is, in fact, a **vascular procedure** requiring deep knowledge of **neuroanatomy and vascular anatomy**.

To safely and effectively perform this surgery, the surgeon must have an **exact understanding of where pelvic nerves run**, how they can be compressed, and how to identify the problem **without performing unnecessary or dangerous dissections**. Equally important is a thorough knowledge of the **pelvic blood vessels** to avoid complications such as **intraoperative hemorrhage**, which can potentially be life-threatening.

Furthermore, to prevent persistent pain after surgery and avoid the need for a second operation, **metal clips should never be used**. Although clips are commonly used in gynecologic or general laparoscopic surgery for closing blood vessels, in the context of pelvic nerves, they can **irritate or even damage the nerves after surgery**. During decompression surgery for vascular entrapment, the **compressing veins must not only be closed but fully resected** - simply clipping them is not enough.

Importantly, this procedure has **no negative impact on fertility or other pelvic organs**. Only the veins compressing the nerves are treated - not the entire pelvic vessels network, which remains richly supplied. This is why a **precise preoperative neuropelveological diagnosis** is essential: to identify the exact nerves involved, their location, and the specific vessels causing compression.

When done correctly, this surgery offers significant pain relief and can be life-changing for women suffering from chronic pelvic nerve pain. But it must be performed by a surgeon who is trained in **neuropelveology**, understands **vascular and nerve anatomy**, and is experienced in **laparoscopic nerve decompression**.

 

**FINAL THOUGHTS**

If you're struggling with unexplained pelvic pain, don’t give up.

What you’re feeling is **real**, and there may be a **very real, very treatable cause** behind it.

✅ Trust your body.  
✅ Ask the right questions.  
✅ Seek specialists who understand pelvic nerves and vascular conditions, a Neuropelveologist - not just gynecology or urology.

 

**We’re Here to Help**

**Possover International Medical Center – Zurich**  
☎️ +41 44 520 3600  
📍 Klausstrasse 4, CH-8002 Zürich  
🌐 [www.possover.com](https://www.possover.com/?hsLang=en)  
📧 mail@possover.com

Let us help you **find the cause of your pain** — and finally start your journey toward healing.

If you or someone you know is struggling with **chronic pelvic pain, pelvic nerve disorders, endometriosis, or consequences of pelvic surgery**, please contact us via email at **international@possover.com** to begin the process. Because we want to avoid the scenario where a patient travels to Zurich, only to discover that we may not be able to offer help for their specific situation, we have **Pre-Consultation Zoom process**. **How does it work?**

1. Patients will first receive a **Pre-Consultation Form**.
2. Based on the information provided, we will assess whether a Zoom consultation is necessary.
3. If indicated, we will schedule a **Pre-Consultation Zoom Call** to help determine if a full evaluation at our center makes sense for your case.

 

[View full post](https://blog.possover.com/en/pelvic-pain-vascular-entrapment)

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